Loading

But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and will give you a complete account of the system and expound the actual teachings of the great explore

Contact Info

    shape
    shape

    Venlor

    Waldo C. Feng, MD, PhD, FACS, FAAP

    • Clinical Professor, University of Nevada Medical School
    • Chief of Urology, Sunrise Hospital and Children? Medical
    • Center, Las Vegas, Nevada

    In these circumstances the R codes have been lesions of the brachial plexus anxiety group therapy generic venlor 75 mg without a prescription, which used to occupy provided for relative completeness but will rarely anxiety symptoms 247 cheap 75 mg venlor, if Group X anxiety chat rooms order venlor with mastercard, have been placed with pain in the shoulder anxiety symptoms racing thoughts venlor 75mg mastercard, ever, be required. Inevitably some of the numbering within If there is no code: groups has also been changed, but as far as possible the (a) check the introduction to see if the item has original numbering has been retained so as to require the been rejected. The following use of complete challenge because of the existence of many codes is particularly noteworthy. The editors will be pleased In the case of spinal and radicular pains, the to advise on the possibility of assistance in this respect. X5c (vascular) If three or more major sites are involved, code first digit as 9: 903. Primary Headache Syndromes, Vascular Disorders, and Cerebrospinal Fluid Syndromes 1. Similarly a lumbar pain which extended to the sacrum or a sacral pain which extended to a minor In this section, both spinal pain and radicular pain portion of the lower limb above the knee would be are considered. Definitions of spinal pain and related adequately qualified by the principal area in which it is phenomena are offered first, followed by principles felt. If two areas are substantially involved, then both related to spinal pain and a comment on radicular pain areas are required to be identified and diagnoses listed and radiculopathy. This schedule is intended from anywhere within the region bounded superiorly by to be comprehensive and includes numerous categories the superior nuchal line, inferiorly by an imaginary and coded items that are not described. Other elements, transverse line through the tip of the first thoracic the more common and chronic with respect to pain, are spinous process, and laterally by sagittal planes described in detail later in the body of the text according tangential to the lateral borders of the neck. Cervical pain may be subdivided into upper cervical the coding system and schedules provide categories pain and lower cervical pain by subdividing the above for both spinal pain and radicular pain when they are region into two equal halves by an imaginary transverse associated with each other or when they occur plane. A diagnosis for each should be made as nuchal line and an imaginary transverse line through the required with the suffix S or R as appropriate, and C tip of the second cervical spinous process can be when both occur. Subsequent to the schedule of classifications for the Thoracic Spinal Pain: Pain perceived as arising cervical and thoracic regions a more detailed description from anywhere within the region bounded superiorly by of radicular pain and radiculopathy is provided. Pain located over the posterior chest wall but lateral to the above region is best described as posterior chest wall pain to distinguish it from thoracic spinal pain. The location of the pain Lumbar Spinal Pain: Pain perceived as arising can be described in terms similar to those used to from anywhere within a region bounded superiorly by an describe the five regions of the vertebral column, i. The following descriptions Pain located over the posterior region of the trunk therefore apply only to the description of symptoms and but lateral to the erectores spinae is best described as not to their cause. Coccygeal Pain: Pain perceived as arising from the region defined by the location of the coccyx. Cervico-Occipital Pain: Pain perceived as arising in the cervical region and extending over the occipital region of the skull. Cervico-Thoracic Pain: Pain perceived as arising from a region encompassing or centered over the lower quarter of the cervical region as defined above and the upper quarter of the thoracic region as defined above. Thoraco-Lumbar Pain: Pain perceived as arising from a region encompassing or centered over the lower quarter of the thoracic region as described above and the upper third of the lumbar region as described above. Lumbosacral Pain: Pain perceived as arising from a region encompassing or centered over the lower third of the lumbar region as described above and the upper third of the sacral region as described above. Combined States: Spinal pain not satisfying either the primary or conjunctional descriptors defined above but otherwise encompassing more than one spinal region should be described in composite forms. This definition, however, becomes ambiguous in situations where it is unclear where one region of the body ends and an adjacent region begins. Consequently, without detracting from the intent of the above definition, referred pain can be defined more strictly in neurological terms as pain perceived as arising or occurring in a region of the body innervated by nerves or branches of nerves other than those that innervate the actual source of pain. Referred pain may thus occur in a region that is either remote from or directly contiguous with the source of pain, but the two locations are distinguishable on the basis of their different nerve supply. In the context of spinal pain, referred pain may occur in the head (Campbell and Parsons 1944; Feinstein et al. Referred pain in the lower limb may be qualified using standard anatomical terms that describe its Scapular Pain: Pain perceived as arising topographic location, viz. Physiology: the anatomical basis for spinal Posterior Shoulder Pain: Pain focused over the referred pain appears to be convergence. In the absence of any further according to the topographic segment encompassed localizing information, the brain is unable to determine using standard anatomical definitions, viz. Convergence is typically segmental in nature, in that should be described in such terms. Its exact topographic referred pain is perceived as arising from those regions location can be specified by enunciating the ribs that it spans. However, convergence may also occur between qualified using established terminology describing the regions of the abdomen, viz. In (see also Radicular Pain and Radiculopathy, cases of doubt no implication should be made and the below) pain should be described as pain in the lower limb. In this section, individual descriptions of the quality Ectopic activation may occur as a result of mechanical of pain have not been presented throughout the deformation of a dorsal root ganglion, mechanical descriptions of syndromes. This is because pain in the stimulation of previously damaged nerve roots, back tends not to discriminate much among the different inflammation of a dorsal root ganglion, and possibly by diagnostic groups. The following general characteristics ischemic damage to dorsal root ganglia (Howe et al. Acute back pain is often cramping or knifelike, but Ectopic activation results in pain being perceived as may be merely dull or aching. Chronic back pain without a radicular Radicular pain differs from referred pain in several component is generally aching, dull, or burning or any respects. It also tends to be the disease processes that cause radicular pain are made worse by movement. Cervical angina, Spine, I (1976) 28Smyth and Wright 1959; McCulloch and Waddell 1980). While also perceived deeply, radicular pain nevertheless has a cutaneous quality in proportion to the number of Campbell, D. It stems from an era when the mechanisms joint pain patterns I: a study in normal volunteers, Spine, 15 of referred pain and radicular pain were poorly (1990)453-457. However, these entities have been included in the Principles schedule for completeness. The symptom of spinal pain should be described in For conditions that are considered still controversial terms of its location and nature using the definitions or unproven, the Committee has formulated criteria that supplied on pages 11 and 12; these descriptions, should be fully satisfied before the diagnosis is ascribed. The Committee also accepts the use of such diagnoses As far as possible, the actual diagnosis of spinal on a presumptive basis without the criteria being pain should be expressed simultaneously along two axes: satisfied. In adopting this stance, the Committee seeks to an anatomic axis specifying the structure that is the mediate contemporary controversies by on the one hand source of pain, including its regional or segmental acknowledging novel or controversial entities while on location, and a pathologic axis specifying the the other hand outlining criteria that if satisfied should pathological basis for the cause of pain. In some cases both forms of pain In this way, the following taxonomy is designed not may stem from the one lesion and a single diagnosis can to be limiting or prescriptive but to provide options be formulated. Technically, radicular separate but related causes; both should be enunciated, pain is not a spinal pain, for it is not perceived in any. However, it posterior thigh and calf due to stenosis of the L4-5 is mentioned in the context of spinal pain for not intervertebral foramen. It is, however, dorsal root ganglion mechanically or indirectly illegitimate to diagnose or classify any form of spinal compromise the spinal nerve and its roots by causing pain as radicular pain or in terms relating to radicular ischemia or inflammation of the axons. Radicular pain in isolation is strictly a pain include: problem of the affected limb or body wall segment. Foraminal stenosis due to vertical subluxation of the When associated with spinal pain, the spinal pain intervertebral joint, osteophytes stemming from the warrants an independent classification to which the zygapophysial joint or intervertebral disk, buckling of classification of the radicular pain may then be the ligamentum flavum, or a combination of any of appended. Foraminal stenosis due to miscellaneous disorders of with spinal pain, but radiculopathy involves loss of the zygapophysial joint such as articular factures, conduction in sensory or motor axons, or both, in a slipped epiphysis, ganglion, joint effusion, and nerve root, and there is no evidence that such conduction synovitis. Prolapsed intervertebral disk acting mechanically as a radiculopathy that may be associated with it. Prolapsed intervertebral disk material that elicits an independently, supplemented if required by a inflammatory reaction in the vertebral canal that classification of the radiculopathy. Radiculitis caused by inflammatory exudates leaking extent or distribution of referred pain has no bearing on from an intervertebral disk in the absence of frank the underlying cause of the spinal pain.

    75mg venlor sale

    Tell your doctor if you have ever abused or been dependent on alcohol anxiety synonyms venlor 75 mg with mastercard, prescription medicines or street drugs anxiety symptoms headaches order cheap venlor line. Symptoms include more outgoing or aggressive behavior than normal anxiety jaw clenching quality venlor 75 mg, confusion anxiety symptoms weight loss buy venlor with visa, agitation, hallucinations, worsening of depression, and suicidal thoughts or actions. Inactive Ingredients: calcium phosphate, colloidal silicon dioxide, croscarmellose sodium, hypromellose, lactose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, titanium dioxide, and triacetin. Access to the Obesity Algorithm content and/or permission for extensive quoting or reproducing excerpts and for the reproduction and use of copyrighted text, images, or entire slides will not be granted until the requestor has signed the copyright consent and permission agreement available at This 2016-2017 version of the Obesity Algorithm incorporates worldwide input, as well as interim scientific and clinical trial data. The Obesity Algorithm is listed by the American Board of Obesity Medicine as a suggested resource and study-aid for the obesity medicine certification exam. Reference/s: [2,3] Obesity Health Care Office Environment Clinicians and staff should be trained to avoid hurtful comments, jokes, or being otherwise disrespectful, as patients with obesity may be ashamed or embarrassed about their weight. Reference/s: [1] Fat Mass Disease: Abnormal and Pathologic Physical Forces 41 obesitymedicine. Treatment of Adult Patients with Overweight or Obesity Medical Management and Coordination Nutrition Physical Activity Behavior Therapy Pharmacotherapy Bariatric Surgery 125 Obesity Algorithm. Reference/s: [1] Nutritional Therapy for Obesity Factors related to improved outcomes: Evidence-based Quantitative Patient adherence Patient preference Qualitative 144 Obesity Algorithm. Reference/s: [1] Choosing Nutritional Therapy for Obesity the most appropriate nutritional therapy for weight loss should be safe, effective, and one to which the patient can adhere. Reference/s: [1] Nutritional Therapy for Obesity Energy consumption intended to cause negative calorie balance and loss of fat mass Low-calorie diets: Very low-calorie diets: 1,200-1,800 kcal/day Less than 800 kcal/day Physician Restricted supervision Restricted fat diet carbohydrate diet recommended Recommended Low-glycemic diet: for shorter Low-fat diet: durations <30% fat calories Low-carbohydrate Commercial diet shakes, bars, Very low-fat diet: 50-150 grams/day and soups <10% fat calories which replace Very low meals. The Mediterranean Diet has the most consistent and robust scientific support in reducing atherosclerotic cardiovascular disease risk. Reference/s: [146-148] Atkins Diet the Atkins Diet is illustrative of a carbohydrate-restricted nutritional intervention which promotes utilization of fat for energy and generates ketosis, which may reduce appetite. Reference/s: [149-151] Ornish Diet the Ornish Diet is illustrative of a fat-restricted nutritional intervention. Reference/s: [155,156] Paleolithic Diet Paleolithic nutritional intervention is based upon a diet pattern presumed to exist during the Paleolithic period (lasting 3. It differs from some other diets in that it excludes grains, dairy, and processed foods. Reference/s: [157-159] Vegetarian Diet A vegetarian nutritional intervention includes a meal plan consisting of foods that come mostly from plants. Motivational Interviewing: Stages of Change Pre-contemplation Unawareness of the problem Progress Contemplation Thinking of change in the next 6 months Preparation Making plans to change now Action Implementation of change Relapse Restart of unfavorable behavior 171 Obesity Algorithm.

    75mg venlor sale. If Jeff Inherited a Fortune - WWJD (2019).

    venlor 75 mg low cost

    On examination there was a swelling the size of a golf ball attached to her tongue anxiety 4 weeks after quitting smoking purchase venlor from india. A biopsy was arranged and confrmed that the swelling was a late stage squamous cell carcinoma anxiety high blood pressure venlor 75mg overnight delivery. This was not related to her stay in hospital but highlights the Squamous cell carcinoma importance of mouth care assessments for all vulnerable patients anxiety panic attacks buy venlor online now. This decline in cognitive function frequently Patients with cognitive impairment such as learning causes behavioural changes that directly affect oral health anxiety symptoms panic attacks purchase venlor uk. This population group the energy or be able to speak up when they have oral often have heavily treated teeth (lots of fllings, crowns, problems. Hospital staff should be aware of signs that may bridges and even implants that need increasing care with suggest that the patient has problems with their mouth: age). There is also an increased risk of dry mouth due to medication and mouth breathing. Studies have shown that oral plaque can harbour respiratory pathogens (Scannapieco, Stewart and Mylotte, 1992) increasing their 18. There the oral health of people with moderate to severe learning is a wealth of knowledge and clear guidelines for hospitals, disabilities has been found to be poorer than that of the intensive care wards and nursing staff to ensure that general population. People with learning disabilities have these critical care patients receive the correct mouth care been found to have poorer oral hygiene, consistently measures to prevent further impact to their health (Tablan higher rates of untreated decay (Anders and Davies, 2010) et al. Pneumonia carries a risk of and are more likely to have severe gum disease when mortality of up to 25% (cited in Sjogren et al. There are severe learning disabilities may require more assistance or be many devices such as masks, fasteners and bite blocks on fully dependent on another individual for all mouth care. This gel reduces the risk of ventilated-associated pneumonia can cause a rapid development of decay and gum disease by 40% (Shi et al. A more recent study has and can result in dental infection and pain (Brennan and concluded that the use of chlorhexidine for cardiac surgery Strauss, 2014). In addition to their poor are reviewing their policies on the use of chlorhexidine. This may include daily reminders and encouraging patients at different times of the day when they are more receptive. A mouth guard or fnger reduced sugar diet are important for these patients to prop may also be useful minimise their risk of decay. More than a third of stroke patients reported diffculty with tooth cleaning; the degree of physical disability following 18. Furthermore, the physical diseases and illnesses and may impact on oral health in a weakness, lack of coordination and the cognitive problems number of ways. Mobility problems can also mean including stroke, and is most frequently seen in elderly that patients have diffculty accessing a sink area and patients. The reduced oral clearance (removing food prevent them from carrying out toothbrushing or from the mouth) in such patients negatively impacts their denture care. Cognitive Impairment in Older Adults and Oral Health Considerations: Treatment the oral health of end of life and palliative care patients is and Management. Poor oral health can have a big Hunter, V R, Clarkson, E J, Fraser, W H, MacWalter, S R. Mouth care for palliative care patients should seek to make the patient as comfortable as possible in the least invasive way: Karjalainen, S. Journal of Public suctioning or a toothbrush/MouthEze cleanser Health Dentistry; 74(2): 127-138. No toothbrushing was being carried out as nursing staff said that they were worried that the patient would not be able to tolerate this very well. A Mouth Care Recording Pack was completed and nursing staff were reminded of the importance of recording all mouth care on a daily basis. On review, the patient was receiving the appropriate dry mouth treatment every 2 hours. Toothbrushing was being carried out daily and this was being appropriately recorded. Nursing staff reported that the patient now appeared to be more comfortable and was very welcoming of mouth care when given. There are several companies that market small-headed toothbrushes for hospitalised/intensive care patients. Some hard bristled toothbrush for a palliative care patient with a hospital occupational therapists will also be able to make sore mouth and limited mouth opening. The following section describes recommendations for mouth care products based on experiences of the Mouth Care Three-headed toothbrush Matters team. The team have found for consistency and A three-headed toothbrush (see page 69) can be used for compliance it is better to limit the number of products (for patients whose cooperation with toothbrushing is limited. However, they encouraged to bring in their own mouth care products are not as effective at removing dental plaque as normal into hospital or ask a family member or carer to do this manual or electric toothbrushes and should only be used for them. Three-headed toothbrushes should be used with toothpaste and placed over the teeth. Without a light source it is impossible to fully water from the mouth during toothbrushing. This may be assess the mouth and many conditions especially at the particularly useful in unconscious or intubated patients who back of the mouth will be missed. They should be used in the same way as a manual toothbrush using circular motions to clean all tooth surfaces. However, if a non-foaming toothpaste is used the need for aspiration toothbrushes is less. They often have Ideally toothbrushes need to be stored so that the head small heads, which are ideal for cleaning all areas of the can be air-dried following use. If the toothbrush has a rotating action, circular number of spores in the air this is not feasible. Ideally this would be in a covered towards the gum margin and held there before moving container for air circulation rather than a plastic bag.

    discount venlor 75mg without prescription

    Confounders considered included marital status anxiety xyrem order venlor paypal, smoking (age started smoking anxiety symptoms breathing order cheapest venlor and venlor, average number of cigarettes anxiety management order 75mg venlor with visa, pipe or cigars smoked per day anxiety fatigue buy generic venlor pills, total years smoked), and ethnicity. Controls were frequency-matched by sex and age to the combined distribution of the stomach and esophagus cases. Limitations: the major limitation Data analysis: Unconditional was the large proportion of proxy Glyphosate analysis (only conducted logistic regression. Most of the among male farmers) included 17 cases analyses by sex and respondent associations observed were and 32 controls among farmers compared type (selfversus proxy-reported) limited to proxy respondents. Among these, selfAdjustments: Age, sex, and reported respondents included respondent type. Controls were frequency-matched by sex, age, and vital status to the combined distribution of the cases. Glyphosate analysis included 36 exposed registries, except in Quebec, and 321 unexposed cases and where hospital ascertainment was 147 exposed and 1,359 unexposed used. Data analysis: Conditional logistic Potential controls were selected randomly regression. Analyses were control interviews that were with and 786 unexposed cases and separately conducted with or proxies. House and garden pesticide use: Glyphosate analysis included 51 exposed and 747 unexposed cases and 76 exposed and 1,099 unexposed controls. Analysis included 28 exposed and 410 unexposed cases and 75 exposed and 1,066 unexposed controls excluding proxy respondents. Randomly-selected, population-based controls were frequency-matched within a state. Set 3: 40,719 applicators, additionally excluded those missing data on Sets 1 and 3: Age at enrollment, additional pesticide use. Potential inaccuracies in the and 49 controls who used glyphosate evaluation of pesticide exposure herbicide compared to never-farmers Data analysis: Unconditional could lead to exposure (243 cases and 547 controls). Multiple statistical comparisons make it Controls were a population-based, Adjustments: Vital status, age, difficult to separate real stratified sample of white men state, tobacco use, family history of association from chance findings. Limitations: Small number of cases and controls, multiple 173 cases and 650 frequency-matched Data analysis: Logistic models statistical comparisons, and controls from random digit dialing, adjusted for vital status and age. Glyphosate analysis included 11 exposed and 162 unexposed cases (n=173) for multiple myeloma and 40 exposed and 610 unexposed controls (n=650). Glyphosate analysis included Adjustments for age, gender, four exposed B cell lymphoma cases education, center. Glyphosate analysis included Registry from 1981 to 1983 from 36 exposed and 614 unexposed cases males fi30 years of age. In (n=650) and 61 exposed and Minnesota, cases were ascertained 1,872 unexposed population based from a surveillance system of matched controls (n=1,933). Minnesota hospitals and pathology laboratories from 1980 to 1982 in males fi30 years of age. In Kansas, cases were randomly selected from statewide cancer registry from males fi21 years of age. Data analysis: Two models were used: (1) standard logistic regression and (2) hierarchical regression adjusted for age and study site. December 1, 1999 and April 30, Ever (>10-year latency): pesticide exposure, no 2002. Data analysis: Conditional logistic regression analysis adjusted for both univariate and multivariate. Excluding proxy >2 days/year (exclude proxies): respondents, analysis included Data analysis: Logistic regression. Glyphosate analysis included from September 1, 1991 to Potential for recall bias and for 38 exposed and 278 unexposed December 31, 1994. Low response rates province of residence, personal resulted in inability to evaluate and family medical history. Cases identified through 684 controls for non-asthmatic nonNebraska Lymphoma Study group farmers (reference), 53 cases and and area hospitals between July 91 controls for non-asthmatic farmers, 1983 and June 1986 (n=346). Data analysis: Unconditional logistic regression adjusted for these data were used in the pooled age, state, vital status. December 31, 1991 from cancer for exposure, but demonstrated a registries for five providences, in Exposure >2 days/year: dose-response relationship. Limitations: Potential for recall cases (n=517) and 133 exposed and bias and misclassification of 1,373 unexposed age-matched controls Data analysis: Conditional logistic pesticide exposure. Because of limited statistical power, analysis was restricted to exposure that at least 1% of respondents ever used. Multiple Glyphosate analysis included 4 exposed Swedish Cancer Registry from comparisons may result in some and 107 unexposed cases (n=111) of 1987 to 1992. These data were used in pooled Data analysis: Logistic regression analysis by De Roos et al. Glyphosate analysis included 32 exposed and 310 unexposed cases Data analysis: Conditional logistic (n=342) and 133 exposed and regression adjusted for age, 1,373 unexposed controls (n=1,506). The epidemiological studies on the association between glyphosate use and solid-type tumors are presented in Table 2-7. Overall, these studies did not detect a statistically significant association between glyphosate use and all cancer types studied, including melanoma, childhood cancers, soft tissue sarcoma, colorectal cancer, and cancers of the lung, oral cavity, colon, rectum, pancreas, kidney, prostate (including total prostate and aggressive prostate cancers), testes, breast, bladder, stomach, and esophagus. A statistically significant association with glyphosate use and solid tumors was reported in one study. Overviews of epidemiological studies that focused on the association between glyphosate use and lymphohematopoietic cancers are presented in Table 2-8. A majority of the studies did not report statistically significant associations between glyphosate use and many of the lymphohematopoietic cancer subtypes. These statistically null associations were reported for the following subtypes: all lymphohematopoietic cancers (Andreotti et al. However, in a letter to the editor, Sheppard and Shaffer (2018) argued that the statistical procedure used by Andreotti et al. Therefore, the results of the analysis may have been biased towards the null (Sheppard and Shafer 2019). Results for risk of multiple myeloma and self-reported glyphosate use or exposure from individual studies summarized in Table 2-8 and the meta-analysis summarized in Table 2-6 are plotted in Figure 2-5. Groups of weanling Sprague-Dawley rats (50/sex/group) were administered glyphosate technical (98. Based on body weight and food consumption data, concentrations of glyphosate technical were adjusted to achieve oral doses of 0, 3. Incidences of testicular interstitial cell tumors in the control, low-, mid-, and high-dose male rats were 0/50 (0%), 3/50 (6%), 1/50 (2%), and 6/50 (12%), respectively (Table 2-9). Although the incidence in the mid-dose group was less than that in the low-dose group, trend analysis revealed a significant trend (p=0. Incidences of thyroid c-cell tumors (adenoma, carcinoma, combined adenoma or carcinoma) in the female rats are presented in Table 2-9. An increased incidence of thyroid c-cell carcinomas in female rats approached statistical significance (p=0. The combined incidence of combined c-cell carcinomas or adenomas was not significantly increased (9/47 high-dose females versus 6/47 controls), and time-to-tumor analysis revealed no sign of a treatment-related effect. Historical control incidences of spontaneous thyroid c-cell tumors in female Sprague-Dawley rats were as high as 17%. Incidences of Selected Tumors in Sprague-Dawley Rats Administered Technical Glyphosate (98. Based on mean body weight and food consumption data, estimated glyphosate doses to controls and low-, mid-, and high-dose groups were 0, 89, 362, and 940 mg/kg/day, respectively, for the males and 0, 113, 457, and 1,183 mg/kg/day, respectively, for the females. As shown in Table 2-10, low-dose (but not midor high-dose) males exhibited significantly increased incidences of pancreatic islet cell adenoma (p=0.

    References

    • Holmes DR, Wester W, Thompson RW, et al: Prostaglandin E2 synthesis and cyclooxygenase expression in abdominal aortic aneurysms, J Vasc Surg 25(5):810-815, 1997.
    • Burwell CS, Rubin ED, Whaley RD, et al. Extreme obesity associated with alveolar hypoventilation: a pickwickian syndrome. Am J Med 1956;21:811.
    • Kim MA, Park KM, Kim SE, Oh MK. Acute symptomatic seizures in CNS infection. Eur J Neurol. 2008;15:38-41.
    • Sydenham E, Dangour AD, Lim WS. Omega 3 fatty acid for the prevention of cognitive decline and dementia. Cochrane Database Syst Rev Published June 2012.