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But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and will give you a complete account of the system and expound the actual teachings of the great explore

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    Bradley M. Lamm, DPM

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    Other conditions are defned as those conditions that coexist or develop during the episode of health care and affect the management of the patient depression test learnmyself order zyban 150 mg fast delivery. Conditions related to an earlier episode that have no bearing on the current episode should not be recorded mood disorder with depressive features purchase 150 mg zyban with visa. By limiting analysis to a single condition for each episode anxiety and blood pressure buy cheap zyban on-line, some available information may be lost depression test child cheap 150 mg zyban visa. It is therefore recommended, where practicable, to carry out multiple-condition coding and analysis to supplement the routine data. This should be done according to local rules, since no international rules have been established. This information should be organized systematically by using standard recording methods. A properly completed record is essential for good patient management and is a valuable source of epidemiological and other statistical data on morbidity and other health-care problems. Uncertain diagnoses or symptoms If no defnite diagnosis has been established by the end of an episode of health care, then the information that permits the greatest degree of specifcity and knowledge about the condition that necessitated care or investigation should be recorded. This should be done by stating a symptom, abnormal fnding or problem, rather than qualifying a diagnosis as possible, questionable or suspected, when it has been considered but not established. Contact with health services for reasons other than illness Episodes of health care or contact with health services are not restricted to the treatment or investigation of current illness or injury. Episodes may also occur when someone who may not currently be sick requires or receives limited care or services; the details of the relevant circumstances should be recorded as the main condition. Multiple conditions Where an episode of health care concerns a number of related conditions. If there are a number of such conditions, with none predominating, then a term such as multiple injuries or multiple crushing injuries should be recorded alone. Conditions due to external causes When a condition such as an injury, poisoning or other effect of external causes is recorded, it is important to describe fully both the nature of the condition and the circumstances that gave rise to it. Treatment of sequelae Where an episode of care is for the treatment or investigation of a residual condition (sequela) of a disease that is no longer present, the sequela should be fully described and its origin stated, together with a clear indication that the original disease is no longer present. Where multiple sequelae are present and treatment or investigation is not directed predominantly at one of them, a statement such as sequelae of cerebrovascular accident or sequelae of multiple fractures is acceptable. Whenever possible, a record with an obviously inconsistent or incorrectly recorded main condition should be returned for clarifcation. The guidelines given below are for use when the coder may be unclear as to which code should be used. The preferred code indicates the main condition for single-cause analysis and an additional code may be included for multiple-cause analysis. Coding of conditions to which the dagger and asterisk system applies If applicable, both dagger and asterisk codes should be used for the main condition, since they denote two different pathways for a single condition. The categories can be used in the normal way for other episodes of contact with health services. If, after an episode of health care, the main condition is still recorded as suspected, questionable, etc. This is acceptable since the patient was obviously admitted to deal with the immediate emergency only. Coding of multiple conditions Where multiple conditions are recorded in a category entitled Multiple. Such combination categories should be used as the main condition where appropriate information is recorded. The Alphabetical Index indicates where such combinations are provided for, under the indent with, which appears immediately after the lead term. Two or more conditions recorded under main condition may be linked if one of them may be regarded as an adjectival modifer of the other. Example 8: Main condition: Renal failure Other conditions: Hypertensive renal disease Code to hypertensive renal disease with renal failure (I12. Insulin-dependent diabetes Other conditions: Hypertension Specialty: Ophthalmology Code to insulin-dependent diabetes with ophthalmic complications (E10. Example 12: Main condition: Non-insulin-dependent diabetes mellitus Other conditions: Hypertension Rheumatoid arthritis Cataract Specialty: General medicine Code to non-insulin-dependent diabetes without complications (E11. Note that in this example the linkage of cataract with diabetes must not be made since they are not both recorded under main condition. Coding of external causes of morbidity For injuries and other conditions due to external causes, both the nature of the condition and the circumstances of the external cause should be coded. The preferred main condition code should be that describing the nature of the condition. Example 13: Main condition: Fracture of neck of femur caused by fall due to tripping on uneven pavement Other conditions: Contusions to elbow and upper arm Code to fracture of neck of femur (S72. The external cause code for fall on same level from slipping, tripping or stumbling on street or highway (W01, place of occurrence 4) may be used as an optional additional code. The external cause code for exposure to excessive natural cold at home (X31, place of occurrence 0) may be used as an optional additional code. The external cause code for antiallergic and antiemetic drugs causing adverse effects in therapeutic use (Y43. The external cause code for overexertion and strenuous, repetitive movements at sports and athletics area (X50, place of occurence 3) may be used as an optional additional code. The preferred code for the main condition is, however, the code for the nature of the sequela itself, to which the code for Sequelae of. Where a number of different very specifc sequelae are present and no one of them predominates in severity and use of resources for treatment, it is permissible for the description Sequelae of. Note that it is suffcient that the causal condition is described as old, no longer present, etc. Most body-system chapters also contain categories for conditions that occur either as a consequence of specifc procedures and techniques or as a result of the removal of an organ. When postprocedural conditions and complications are recorded as the main condition, reference to modifers or qualifers in the Alphabetical Index is essential for choosing the correct code.

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    Societal mood disorder dsm code purchase zyban mastercard, Ethical and Legal Considerations for Diagnostics Technological advances can challenge depression in older adults buy zyban online, and sometimes outstrip depression test color purchase zyban 150 mg, social depression quest steam zyban 150 mg without prescription, ethical and legal conventions. The collection, use and interpretation of personal diagnostic information poses such challenges today. The confidentiality of diagnostic information, the psychological effects of predictive diagnostics, decision-making following testing and unequal access to certain diagnostic and treatment modalities reflect some of the main considerations associated with existing and emerging diagnostic tests. This section covers key aspects of the mutual effects of the diagnostics industry and broad social, ethical and legal constructs pertaining to . Advances of the electronic age have renewed and reframed debate on the importance of confidentiality and the protection and privacy of patient data. Such weaknesses may include barriers to information dissemination, potential 365 While protected to some extent by the Health Insurance Portability and Accountability Act, electronic medical records and other electronic health information/communications systems that contain confidential patient specific information may not provide sufficient safeguards ensuring that such information cannot be obtained or inappropriately used by employers, health plans and unauthorized others. The Genetic Nondiscrimination Act of 2005, passed in February 2005, bolsters established patient protections and reduces the risks of misuse of genetic and other health information in determining eligibility for employment, scope of health insurance coverage, etc. The extensive data exchange among health insurers, providers and employers, along with the escalating cost of insurance premiums, raise concerns over the potential for employment termination or denial or other limitation of insurance coverage due to unauthorized disclosures of diagnostic information. Protection of Genetic Information Protection of genetic information and prevention of potential discriminatory practices based on knowledge of genetic disorders is of increasing concern. As such, these policies are not adequate for addressing the challenges related to genetic discrimination. Furthermore, state policies often are contradictory or nonspecific to these issues, making protection against genetic discrimination difficult. The Genetic Information Nondiscrimination Act of 2005 was approved by the House and Senate with the goal of establishing legal protections for patients to encourage use of genetic screening and testing. National health information privacy regulations under the health insurance portability and accountability act. Proponents of this legislation argued that, without such legislation, providers, payers and employers could be placed at greater risk for litigation (and associated costs) if actions based on knowledge of genetic predisposition or health status were deemed inappropriate by patients. Others argued that special protection could precipitate many of the problems of concern to supporters of such legislation. Providing special protection to genetic information will often be unfair because it treats people facing the same social risks differently based on the biological cause of their otherwise identical health conditions. Why, for example, should a woman who has developed breast cancer of genetic origin. Even diseases that are solely genetic are not inherently special so as to give rise to unusual claims to legal protection. Indeed, it is conceivable that genetic illnesses are less in need of legal protection than sexually transmitted diseases, which often carry a stigma arising from the perception that they are just desserts for voluntary behavior. On a practical level, we must be cautious that the very people whom policy makers hope to encourage to take advantage of genetic testing may become more reluctant because of the heightened focus on its exceptional nature. Treating genetics as distinct from the rest of medicine may enhance the stigma of genetics testing, even as legislators attempt to remove its stigmatizing effects. This can create public fears and misapprehensions about genetics that could discourage individuals from seeking testing and treatment, and thwart future scientific progress. Conversely, by focusing only on genetics information, legislators may convey the perception that the public need not worry about the confidentiality of other kinds of medical information, fostering complacency in an area where insufficient protections may exist. The National Council on Disability, an independent federal agency reporting directly to the President and Congress on. Public health surveillance of genetic information: ethical and legal responses to social risk. Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease. The misuse of genetic information not only excludes qualified individuals from employment and denies insurance coverage to individuals without justification, but also undercuts the fundamental purposes of genetic research. Such research has been undertaken with the goals of early identification, prevention and effective treatment of disease. These goals will be undermined if fear of discrimination deters people from genetic diagnosis and prognosis, makes them fearful of confiding in physicians and genetic counselors, and makes them more concerned with loss of a job or insurance than with care and treatment. Diagnostics companies could be reluctant to invest in R&D for these products due to subdued levels of demand, even if they have potential for societal benefit. As gene-based and other diagnostics emerge, further debate of their utility and implications will inform their incorporation into practice and related regulatory, payment, and legal policies. In some cases, the knowledge of disease risks or health status can have significant psychosocial impacts on patients and their families. As diagnostic tests that identify individual risk of developing disease become more sophisticated and accessible, the societal impact of predictive testing merits close attention. There are benefits and risks associated with testing for health risks of eventual undesirable health outcomes in currently healthy individuals. Drawbacks to the information provided by predictive diagnostics may include psychological distress and behavioral changes for patients and their families and discrimination based on knowledge of disease risk and potential related psychosocial ramifications. Diagnostic testing causes anxiety, distress and concern in some patients, especially in cases where they do not clearly understand the meaning of test results or are inadequately informed about them. Psychological impact of human papillomavirus testing in women with borderline dyskaryotic cervical smear test results: cross sectional questionnaire study. Psychological Effects the psychological effects on individuals who currently are healthy but learn of a predisposition to developing a disorder can be profound. Yet, despite the potential for these serious psychological effects, many patients do not receive such counseling prior to diagnostic testing for a serious or debilitating illness. It is reported that only 16% of individuals who undergo cancer susceptibility testing receive this type of information prior to testing. Individuals may experience discrimination and feel isolated or alone as the behaviors and perceptions of others, even close family members, sometimes change following knowledge of diagnosis. Stigma and misunderstanding can lead to downstream effects, such as loss of marriage, reduced productivity and decreased quality of life, among others. As mentioned above, insufficient access to counseling services also inhibits patients and family from receiving valuable input for addressing the non-medical challenges that certain diseases can pose. Behavioral Effects In addition to psychological impacts, there may be behavior effects associated with diagnostic testing. For some, the behavioral effects resulting from a positive susceptibility test are beneficial, as individuals may make lifestyle changes to improve their health and potentially lower the severity of disease, and perhaps the risk of developing it. In other cases, predictive diagnostics may lead to difficult or insufficiently informed decisions about the best course of action to pursue. For example, a woman who discovers a genetic predisposition to breast cancer may opt for a mastectomy to reduce risk without full consideration of other mitigating risk factors or impact on her quality of life. The use of diagnostics in reproductive medicine exemplifies the beneficial capabilities of diagnostics, as well as the difficult choices resulting from knowledge of this information. For example, individuals who do not want to pass a genetic condition to a child may consider options such as embryo selection. Some parents may use this diagnostic information and choose only those embryos that are free of the condition prior to implantation. Such prenatal testing can provide families with time to prepare medically, financially and emotionally for a child who will have special needs. Ethical debates over preconception and prenatal diagnostic testing continue, particularly regarding testing for conditions for which there is no definitive or effective treatment or conditions that are not life-threatening. The availability and use of diagnostics pose unique considerations for allocation of health services.

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    In this example anxiety vest for dogs order zyban 150 mg line, we will look at graphs of sub-syndromes to see if there are any alerts that may require further investigation depression cake effective 150mg zyban. You can click on any portion of any of the graphs depression webmd purchase zyban cheap, and then click on a data point on the graph to examine the data for a particular day more closely status anxiety order discount zyban on-line. You can also change your date range and other parameters by going to the configuration options. Based on your level of access, you may view and analyze emergency department data, Merlin reportable disease data, Merlin limited view reportable disease data (for hospital users), death records data, and/or Poison Control data. Subsequent sections will explain how to analyze Merlin reportable disease and Poison Control data. For the geography system, you can select hospital region, which will allow you to select a county or grouping of counties. If the age group you want to look at is not one of the pre-set age categories, click on the select age range drop down menu to customize the age or age range. Once you have made all your selections, you can click on time series at the bottom of the page to see a time series graph of the data. You can access your bookmarks later by clicking on the bookmarks tab in the main toolbar. To query the free text chief complaints, 1) Click on query portal in the main toolbar. The purpose of the ^, or wildcard symbol, is to tell the system that you want to see chief complaints with the word(s) enclosed in the ^, plus any other words. Examples of a few free text queries include: Carbon monoxide poisoning: ^carbon^,or,^carbon monoxide^ Fever and stiff neck: ^fever^,and,^stiff neck^,or,^mening^ Pneumonia without mention of aspiration pneumonia: ^pneumonia^,andnot,^aspiration^ 31 To make multiple selections of any of the variables, hold the control key down on your keyboard and select your choices, which will all be highlighted in blue. After you have typed in the free text query and made all the necessary changes to the other fields, you can click on time series at the bottom of the page to see a time series graph of the data. To change your previously made selections, click on the plus sign next to configuration options above the time series graph. Since you would like to look at trends for the entire state, you can leave the geography system as hospital region. It is therefore important to be familiar with the chief complaints from your area to find the best combination of terms that will provide the best results for a query. To look at aggregate data for all the counties, please select all the counties in the region field. Also, select all the age groups if you are not interested in looking at the data for any one age group. Below is one example of a line graph, but many different line graphs and bar charts can be created in the matrix portal. Holding the control key down on your keyboard, click on your syndromes and age groups of choice. By selecting the map view (not shown) you will see a map for the specified syndrome and day you clicked on in the data matrix. This table includes a link the map for each of the alerts, and may be a more efficient way to evaluate the Merlin spatial alerts. To save a search, you type in the name you would like to give the query and click on bookmark page in the top left corner of the page below the main toolbar. Query manager is similar to bookmarks, but it also has other useful features that are not available in the bookmarks. For style, select single, and the system will plot all your selected queries from step 2 on the same chart. For the date alignment, actual dates uses the dates saved with each individual query to run detection on that query. Deleting your saved query: 1) Go into the query manager 2) Click in the checkbox next to the query you would like to delete 3) Click delete at the top of the page to permanently delete the query. Depending on your level of access, you can review the Merlin data, look at trends of reportable diseases, and generate graphs, tables, or maps to be used in reports, presentations, etc. Hospital users please note: You can also access the Merlin reportable disease data, but only through the Merlin Limited View Reportable Disease Data selection in the query portal drop down list. However, the general instructions here still provide a useful guide to accessing the data at your level of access. For geography system, you can select county, which will allow you to view the data for a particular county or grouping of counties. To make multiple selections in the same field, hold the control key down on your keyboard and make those selections. In this example we select reportable disease from the overview parameter drop down menu, because we wanted graphs of each disease selected. The other parameters in the drop down menu allow you to stratify the data by county, diagnosis status, case status, outbreak status, etc. For sharing purposes or to include in reports you can click on download zip file containing all graphs beneath the bar graphs to download and save the graphs to a different location. You can click on the plus sign next to description to see the parameters selected for the most recent query. A few weeks later, the Office of Vital Statistics sends updates to those previously sent records that include the initial free text descriptions of the cause of death. The timeliness of this data source is different in comparison to the other data sources. The categories are defined at the national level, and include the 358, 113, and 130 select cause groups. Please note that the 130 select cause groups are designed for infants, so when you query the system based on this category, customize the age to only those equal to 0. Select initial literal cause of death these are free text cause of death statements that are written on the death certificate and entered into the central database. You can string together a long list of codes using boolean operators like and, andnot, and or between entries, just as you might in the free text queries. A note about querying the coded values using the ^ wildcard symbol: If your intent is to capture all the codes j10, j10. Time series graphs can also be saved to the query manager by typing in a query name in the query name field above the time series graph. One graph is presented as the number of P&I deaths per week, and the other as a proportion of total deaths (observed P&I deaths/total number of deaths)*100). The seasonal baseline and epidemic threshold is calculated for the statewide data using a periodic regression model that incorporates data from the previous 3 years. The link below the two statewide graphs, where it says If you want to investigate more, click here brings the user to a query portal page with the P&I query pre-selected. The user just has to pick the county or counties they would like to look at, and change the time resolution of the data if desired. I t c o v e r s a l l t h e i s s u e s t h a t f a m i l y d o c t o r s, o b s t e t r i c i a n s, p a e d i a t r i c i a n s a n d o t h e r p r a c t i t i o n e r s n e e d t o k n o w, a n d a r e l i k e l y t o b e a s k e d b y f a m i l i e s, f r o m t h e s c i e n t i f i c b a s i s o f i n h e r i t a n c e t o d i s c u s s i o n o f t h e s p e c i f i c d i s o r d e r s. To interpret all the information now available it is necessary to understand the basic principles of inheritance and its chromosomal and molecular basis. All medical students, irrespective of their eventual career choice therefore need to be familiar with genetic principles, both scientific and clinical, and to be aware of the ethical implications of genetic technologies that enable manipulation of the human genome that may have future application in areas such as gene therapy of human cloning. In producing this edition, the chapters on molecular genetics and its application to clinical practice have been completely re-written, bringing the reader up to date with current molecular genetic techniques and tests as they are applied to inherited disorders. There are new chapters on genetic services, genetic assessment and genetic counselling together with a new chapter highlighting the clinical and genetic aspects of some of the more common single gene disorders. A glossary of terms is included for readers who are not familiar with genetic terminology, a further reading list is incorporated and a list of websites included to enable access to data that is changing on a daily basis. In particular, I am indebted to Dr David Gokhale who has re-written chapters 17, 18 and 20, and has provided the majority of the illustrations for chapters 16, 17 and 18. I am also grateful to Lauren Kerzin-Storrar and Tara Clancy for writing chapter 3 and to Dr Bronwyn Kerr for contributing to chapter 11. Numerous colleagues have provided illustrations and are acknowledged throughout the book.

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    Syndromes

    • Constrictive heart failure
    • Fever
    • When nausea or vomiting occur
    • Low blood pressure
    • Hydronephrosis
    • Blood clots
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    Young syndrome

    It supported the concept of developing non-conventional methods at the community level as a method of flling information gaps in individual countries and strengthening their information systems depression test edu order zyban 150mg on line. It was stressed that mood disorder following cerebrovascular accident purchase zyban mastercard, for both developed and developing countries depression zyprexa purchase zyban toronto, such methods or systems should be developed locally and that depression in young adults order generic zyban, because of factors such as morbidity patterns as well as language and cultural variations, transfer to other areas or countries should not be attempted. The main criteria for selection of this name are that it should be specifc (applicable to one and only one disease), unambiguous, as self-descriptive as possible, as simple as possible, and (whenever feasible) based on cause. However, many widely used names that do not fully meet the above criteria are being retained as synonyms, provided they are not inappropriate, misleading, or contrary to the recommendations of international specialist organizations. Eponymous terms are avoided since they are not self-descriptive; however, many of these names are in such widespread use. Hodgkin disease, Parkinson disease and Addison disease) that they must be retained. Each disease or syndrome for which a name is recommended is defned as unambiguously and as briefy as possible. These comprehensive lists are supplemented, if necessary, by explanations about why certain synonyms have been rejected or why an alleged synonym is not a true synonym. Unnecessary duplication will thus be avoided by a coordinated approach to the development of the various components of the family. Several classifcations may, therefore, be used with advantage; and the physician, the pathologist, or the jurist, each from his own point of view, may legitimately classify the diseases and the causes of death in the way that he thinks best adapted to facilitate his inquiries, and to yield general results. A statistical classifcation of diseases must be confned to a limited number of mutually exclusive categories able to encompass the whole range of morbid conditions. The categories have to be chosen to facilitate the statistical study of disease phenomena. A specifc disease entity that is of particular public health importance or that occurs frequently should have its own category. Otherwise, categories will be assigned to groups of separate but related conditions. Every disease or morbid condition must have a well defned place in the list of categories. Consequently, throughout the classifcation, there will be residual categories for other and miscellaneous conditions that cannot be allocated to the more specifc categories. It is the element of grouping that distinguishes a statistical classifcation from a nomenclature, which must have a separate title for each known morbid condition. The concepts of classifcation and nomenclature are nevertheless closely related because a nomenclature is often arranged systematically. A statistical classifcation can allow for different levels of detail if it has a hierarchical structure with subdivisions. A statistical classifcation of diseases should retain the ability both to identify specifc disease entities and to allow statistical presentation of data for broader groups, to enable useful and understandable information to be obtained. The structure has developed out of that proposed by William Farr in the early days of international discussions on classifcation structure. It has stood the test of time and, though in some ways arbitrary, is still regarded as a more useful structure for general epidemiological purposes than any of the alternatives tested. In place of the purely numeric coding system of previous revisions, the Tenth Revision uses an alphanumeric code with a letter in the frst position and a number in the second, third and fourth positions. Most of Volume 1 is taken up with the main classifcation, composed of the list of three-character categories and the tabular list of inclusions and four-character subcategories. The tabular list, giving the full detail of the four-character level, is divided into 21 chapters. Guidance on the appropriate use of the various levels of the classifcation and the tabulation lists is given in Section 5 of this volume. The defnitions in Volume 1 have been adopted by the World Health Assembly and are included to facilitate the international comparability of data. Each chapter contains suffcient three-character categories to cover its content; not all available codes are used, allowing space for future revision and expansion. The remaining chapters complete the range of subject matter nowadays included in diagnostic data. When the same fourth-character subdivisions apply to a range of three-character categories, they are listed once only, at the start of the range. A note at each of the relevant categories indicates where the details are to be found. It indicates the categories into which diagnoses are to be allocated, facilitating their sorting and counting for statistical purposes. It also provides those using statistics with a defnition of the content of the categories, subcategories and tabulation list items they may fnd included in statistical tables. Although it is theoretically possible for a coder to arrive at the correct code by the use of Volume 1 alone, this would be time-consuming and could lead to errors in assignment. The Introduction to the Index provides important information about its relationship with Volume 1. The rules for this selection in relation to mortality and morbidity are contained in Section 4 of this Volume. Others are borderline conditions or sites listed to distinguish the boundary between one subcategory and another. The lists of inclusion terms are by no means exhaustive and alternative names of diagnostic entities are included in the Alphabetical Index, which should be referred to frst when coding a given diagnostic statement. This usually occurs when the inclusion terms are elaborating lists of sites or pharmaceutical products, where appropriate words from the title. General diagnostic descriptions common to a range of categories, or to all the subcategories in a three-character category, are to be found in notes headed Includes, immediately following a chapter, block or category title. Exclusion terms Certain rubrics contain lists of conditions preceded by the word Excludes. These are terms which, although the rubric title might suggest that they were to be classifed there, are in fact classifed elsewhere. An example of this is in category A46, Erysipelas, where postpartum or puerperal erysipelas is excluded. Following each excluded term, in parentheses, is the category or subcategory code elsewhere in the classifcation to which the excluded term should be allocated. General exclusions for a range of categories or for all subcategories in a three character category are to be found in notes headed Excludes, immediately following a chapter, block or category title. Glossary descriptions In addition to inclusion and exclusion terms, Chapter V, Mental and behavioural disorders, uses glossary descriptions to indicate the content of rubrics. This device is used because the terminology of mental disorders varies greatly, particularly between different countries, and the same name may be used to describe quite different conditions. This convention was provided because coding to underlying disease alone was often unsatisfactory for compiling statistics relating to particular specialties, where there was a desire to see the condition classifed to the relevant chapter for the manifestation when it was the reason for medical care. However for morbidity coding, the dagger and asterisk sequence may be reversed when the manifestations of a disease is the primary focus of care.

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    References

    • Kostis JB, Dobrzynski JM: The effect of statins on erectile dysfunction: a meta-analysis of randomized trials, J Sex Med 11:1626n1635, 2014.
    • Demos CH, Beckkloff GL, Donin MN, Oliver PM. Dimethyl sulfoxide in musculoskeletal disorders. Ann NY Acad Sci. 1967;141:517-523.
    • Shapiro AM, Bain VG, Sigalet DL, et al: Rapid resolution of chylous ascites after liver transplantation using somatostatin analog and total parenteral nutrition, Transplantation 61(9):1410n1411, 1996.
    • Marrelli D, Caruso S, Pedrazzani C, et al. CA19-9 serum levels in obstructive jaundice: clinical value in benign and malignant conditions. Am J Surg 2009;198:333-339.
    • Endo I, Gonen M, Yopp AC, et al. Intrahepatic cholangiocarcinoma: rising frequency, improved survival, and determinants of outcome after resection. Ann Surg. 2008;248:84.